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CBD For Nerve Pain Relief
An estimated 7%[40] of the population suffers from neuropathic pain (NP) caused by nerve damage.
Most research associated with CBD’s impact on relieving nerve pain centers around combinations of THC and CBD rather than CBD alone.
Many believe that CBD helps slow pain signals from the nerves to the brain. This is because CBD indirectly stimulates CB1 and CB2 receptors. When these receptors become stimulated, the signals sent from the nerves decrease, resulting in pain relief.
These receptors can also reduce inflammation[41] in the body. Nerve pain is often related to autoimmune disorders and inflammation, so lowering the body’s inflammatory response may also relieve nerve pain.
Additionally, the European Journal of Experimental Medicine[18] highlights that CBD may reduce inflammation and neuropathic pain by targeting the body’s a3 glycine receptors.
In one review[42] from 2017, researchers looked at 11 randomized control trials with around 1,200 patients. They concluded CBD to be a cannabinoid that improved quality of life and provided a small analgesic benefit to those with NP.
However, the review highlights the need for more extensive, well-designed studies to better evaluate the benefits of CBD for NP.
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CBD For Addiction
The report mentioned earlier by the British Pharmacological Society also highlights the ability of CBD to possibly treat substance abuse disorders.
Another study[43] found that 400 µg/dose of inhaled, pure CBD over one week decreased cigarette consumption in smokers. The group consisted of otherwise healthy individuals who were ready to quit smoking.
Additionally, after overnight cigarette abstinence, single doses of 800mg of CBD were effective at reducing the urge for a cigarette. The study concluded that CBD might have a potential effect on motivational aspects of addiction.
One study[44] by the American Journal of Psychiatry found that CBD may also help reduce cue-induced cravings and anxiety in drug abstinent individuals with heroin use disorder. In this study, the only adverse events reported were mild diarrhea, headache, and fatigue. CBD also reduces heart rate and the stress hormone cortisol caused by drug cues.
CBD For Healthy Skin
The use of plant-based treatments to heal skin issues has been around for centuries. Studies find CBD to be no exception. Research shows CBD oils and topicals may be beneficial to treat various skin conditions.
The skin[45] has cannabinoid receptors that regulate oil production in the sebaceous glands. This is one of the main reasons companies have begun to develop CBD-based topical products.
9.1. CBD for Dry, Itchy Skin
Researchers[46] believe CBD can treat skin disorders such as eczema, dermatitis, and psoriasis because of its anti-inflammatory properties.
A 2019 study[47] suggests that CBD may be effective at treating dry, itchy skin. Topical creams containing CBD can also provide moisture to heal cracked and broken skin.
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9.2. CBD for Protecting and Healing the Skin
CBD has powerful antioxidant[48] properties that may repair damage and reduce wrinkles caused by free radicals. The anti-inflammatory[49] and antioxidant properties of CBD may protect skin from harmful damage, promoting healthy skin aging.
It may also be effective at relieving muscle[50] and joint pain when applied directly to the skin.
9.3. CBD for Reducing Acne
One study[48] highlights that CBD is more effective at treating acne than vitamin C and vitamin E alone.
Another study[51] found that CBD is likely effective at treating acne due to its anti-inflammatory properties that decrease oil production. Reducing inflammation of sebocytes that produce oil in the skin may directly target the acne source.
A review[52] from 2016 highlights the possible antifungal and antibacterial properties of the cannabis plant. When applied topically, this may reduce infections associated with acne formation.
CBD For Arthritis
Arthritis[53] affects nearly 58.5 million adults in the United States. Two of the most prevalent types of arthritis are osteoarthritis and rheumatoid arthritis.
According to the Arthritis Foundation[54], CBD users with arthritis often report noticeable pain relief. However, the foundation recognizes the potential positive impact of CBD use. They also acknowledge[55] that there have not been any rigorous trials to verify its effectiveness in treating arthritis. They publicly urge the Food and Drug Administration (FDA) to expedite the study and regulation of CBD products.
An animal study[56] from 2017 highlighted that local administration of CBD might block pain associated with osteoarthritis. In addition, preventative CBD treatment reduced nerve damage and the development of pain in osteoarthritic joints.