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CBD For Lupus
Lupus[57]Ā is an autoimmune disorder. The most common form of lupus is calledĀ systemic lupus erythematosus[58]Ā (SLE).Ā It occurs when the immune system attacks its own tissues and internal organs. This leads to chronic inflammation and tissue damage that can negatively impact many systems in the body.
Current treatment methods for lupus typically target reducing inflammation to alleviate pain.
Research suggests that CBD may alleviate both pain and inflammation, which are two of the most unwanted symptoms associated with lupus.
There is abundant anecdotal evidence from individuals with lupus who claim CBD effectively alleviates symptoms, but we still need additional scientific proof.
According to a study[59] published in 2018 by Cellular Immunology, CBD protected against pathological T-cell invasion after a spinal cord injury. T-cells[60] are part of the immune system and can help the body fight infection. It is thought that abnormal T-cell activity may be involved in lupus as well.
CBD For PTSD
In addition to reducing fear commonly associated with PTSD, CBD may reduce other symptoms related to the disease.
According to a retrospective case series published by the Journal of Alternative and Complementary Medicine[61], CBD proved effective at relieving symptoms and improving nightmares in patients with PTSD. Of note, CBD was combined with traditional treatments such as medications and dietary changes.
Overall, no patients dropped out of the study due to adverse side effects, and they tolerated CBD well.
CBD For Brain Health
When our brain is healthy, we can perform at our peak. A healthy brain is essential for living a long, healthy life.
According to a new systematic review[62] from 2021, 17 studies with 115 subjects were reviewed to measure the effectiveness of CBD on brain function. The review concluded that neuroimaging studies have shown that acute ingestion of CBD improves performance in healthy volunteers and those with an underlying psychiatric disorder.
TheĀ studies[62]Ā found that CBD modulated brain activity, emotional processing, visual processing, and verbal memory compared to the placebo and THC.
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13.1. CBD for Neuroprotection
CBD may have neuroprotective properties that can reduce damage to the brain. According to one review[63] from 2018, CBD might protect the brain by directly affecting the endocannabinoid system and influencing cannabinoids within the body. It also preserves cerebral circulation during ischemic events.
The review[63] also showed that CBD might help with Parkinsonās disease by bonding with ECS receptors and stimulating dopamine production. Dopamine is involved with maintaining attention and focus and enabling the brain to control movement alleviating spasticity.
CBD also increases brain adenosine levels[64]. Adenosine is related to reduced inflammation and neuroprotection.
Additionally, CBD may have neuroprotective[64] effects on individuals with hypoxic-ischemic brain damage. This is because it activates adenosine receptors in the body.
TheĀ studies[64]Ā also found that CBD may lessen the severity of brain damage by reducing neuroinflammation.
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CBD For Alzheimerās
Weāve already mentioned the neuroprotective benefits that CBD offers, but studies also show direct benefits associated with CBD administration on patients with Alzheimerās disease.
According to one recent animal study[65] from 2021, a two-week course of high-dose CBD improved cognition and reduced inflammation associated with Alzheimerās disease.
The study also suggests that CBD may reduce the accumulation of beta-amyloid plaque, which is a hallmark of Alzheimerās disease. Beta-amyloid typically appears in the brain 15-20 years before the onset of the disease, so CBD use could potentially delay the onset of Alzheimerās.
Additionally, there is a currently ongoing study[66] to evaluate the effectiveness of THC-free CBD oil in improving agitation among patients with Alzheimerās disease.
CBD As An Antioxidant
Antioxidants[67] are chemicals that neutralize free radicals and prevent them from causing damage to our bodies. You can be exposed to free radicals from cigarette smoke, harmful household cleaning products, air pollution, and UV rays.
Research[68] shows that CBD is comparable to other common antioxidants found in fruits and vegetables.
Similar to many other plant compounds, CBD works as an antioxidant[69] to reduce oxidative stress. Researchers[70] have linked oxidative stress with many age-related diseases throughout the years, including cardiovascular disease, chronic kidney disease, chronic obstructive pulmonary disease, neurodegenerative diseases, and cancer.
One animal study[71] published by the Journal of the American College of Cardiology further suggests the potential for CBD to work as an antioxidant to reduce oxidative stress and prevent heart damage in diabetic mice