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CBD As An Antipsychotic
High levels of dopamine can cause psychotic symptoms. Antipsychotic medications[72]are thought to work primarily by inhibiting dopamine receptors. However, they are known to cause unpleasant side effects and can be ineffective in some individuals.
Initial clinical trials[73] show that CBD may have antipsychotic effects on patients with psychosis. Neuroimaging research suggests that CBD may benefit patients with psychosis by modulating the brain function in certain regions that are altered in patients with psychosis. Additionally, the only adverse effects reported were mild GI symptoms and fatigue.
According to one systematic review published[74] in 2020, single-dose CBD had a short-term, medium effect on patients with schizophrenia. However, the review noted no impact on short-term cognitive effects in those with psychotic disorders.
CBD For Mood Improvement krt carts websit
Many CBD users report improvement in mood and mood-related disorders. Serotonin is the neurotransmitter primarily related to mood. Low serotonin levels are associated with depression.
According to a study[75] from 2018, CBD may act on multiple brain pathways affecting mood-regulating chemicals such as serotonin. CBD activated serotonin receptors leading to improved mood.
CBD For Heart Health
Heart disease is a growing health problem worldwide. It is one of the leading causes of death[76] in the US. High blood pressure, elevated total cholesterol, and smoking are all key risk factors for heart disease.
While nothing is as important as diet and lifestyle changes to benefit heart health, research shows CBD plays a role in supporting a healthy heart.
As we mentioned earlier, CBD may reduce blood pressure. This is one of the key risk factors for heart disease.
In addition, one animal study[77] showed treatment with CBD reduced oxidative stress and inflammation and prevented heart damage in diabetic mice with cardiomyopathy.
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18.1. CBD for Cholesterol Levels
CBD may also promote heart health by improving cholesterol levels.
One study[78] published in the Journal of Dietary Supplements studied 65 overweight but otherwise healthy women and men. They were given CBD-containing hemp extract or a placebo every day for six weeks. The results showed that those given hemp extract had significantly improved high-density lipoprotein (HDL) levels compared to the placebo. There were no changes in total cholesterol or LDL levels throughout the study.
HDL[79] is known as the “good cholesterol” because it can help remove other forms of cholesterol from your bloodstream. This is because it picks up extra cholesterol in your blood and takes it back to your liver, where it’s broken down and excreted from your body. Having high levels of HDL can reduce plaque buildup in the arteries and reduce the risk for cardiovascular events.
It’s also important to note that, during the study, liver and renal function, in addition to fasting blood lipids and whole blood cell count, and whole blood counts, remained normal with no statistical differences between the two groups.
18.2. CBD to Reduce the Risk of Cardiovascular Disease
Cardiovascular disease[80] is an umbrella term for several different conditions that are commonly caused by atherosclerosis[81]. Atherosclerosis occurs when plaque builds upon the walls of arteries in the body.
As the plaque builds up, it can prevent blood flow and cause a total blockage leading to a heart attack or a stroke.
Coronary artery disease, cerebrovascular disease, and arrhythmia are all considered to be cardiovascular diseases.
Research suggests CBD may be beneficial for the cardiovascular system. In the heart[82], in vivo treatment with CBD has shown to protect against ischemia (lack of blood flow) and cardiomyopathy associated with diabetes.
Another study[83] from 2015 suggests that CBD may prevent strokes by reducing the risk of metabolic syndrome and delaying atherosclerosis.
CBD As An Immunomodulator
A systematic review[84] from 2021 classifies CBD as an anti-inflammatory, immunosuppressive compound with excellent immunomodulatory properties.
The anti-inflammatory properties of CBD may enhance the immune system by reducing inflammation, resulting in a strengthened immune system.